12‐weeks of Aquatic Exercise Training modifies mTOR signaling following Essential Amino Acid + Carbohydrate Ingestion in Older Subjects

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Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.

We recently showed that resistance exercise and ingestion of essential amino acids with carbohydrate (EAA+CHO) can independently stimulate mammalian target of rapamycin (mTOR) signaling and muscle protein synthesis in humans. Providing an EAA+CHO solution postexercise can further increase muscle protein synthesis. Therefore, we hypothesized that enhanced mTOR signaling might be responsible for ...

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Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis.

Ingestion of an essential amino acid-carbohydrate (EAA + CHO) solution following resistance exercise enhances muscle protein synthesis during postexercise recovery. It is unclear whether EAA + CHO ingestion before resistance exercise can improve direct measures of postexercise muscle protein synthesis (fractional synthetic rate; FSR). We hypothesized that EAA + CHO ingestion before a bout of re...

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Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise.

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Lipolytic suppression following carbohydrate ingestion limits fat oxidation during exercise.

This study determined if the suppression of lipolysis after preexercise carbohydrate ingestion reduces fat oxidation during exercise. Six healthy, active men cycled 60 min at 44 ± 2% peak oxygen consumption, exactly 1 h after ingesting 0.8 g/kg of glucose (Glc) or fructose (Fru) or after an overnight fast (Fast). The mean plasma insulin concentration during the 50 min before exercise was differ...

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HIGHLIGHTED TOPIC Regulation of Protein Metabolism in Exercise and Recovery Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis

Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Volpi E, Rasmussen BB. Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis. J Appl Physiol 106: 1730–1739, 2009. First published June 5, 2008; doi:10.1152/japplphysiol.90395.2008.—Ingestion of an essential amino acid-carbohydrate (EAA CHO) solution following resistance exerc...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2008

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.22.1_supplement.753.13